Two elements of this are important - if Akamai is now an 'SME solution' , based on the idea that the big boys like Yahoo!, Google, and BBC 'Project Canvas' (if it lives on after dead Kangaroo) install their own servers with ISPs, then does the big boy solution fall foul of net neutrality?
Well, first, Akamai's network remains the best Content Delivery Network (CDN) out there, in an increasingly competitive market.
Second, should there be FRAND regulation of these caches? FRAND = Fair Reasonable and Non-Discriminatory Access. The idea is that if Google can build such servers - well, add a rack or two - then so should everyone else, if they wish. Obviously this should be paid for by content providers to ensure equality - Disney can't get BT to pay it for the content OR the server.
This is a well-known principle in for instance LLU regulation - so use it for caches too. The little guys will continue to rely on the good old WWW and get there at usual speed. Or have I missed something?